Increased immune activation during and after physical Eexercise
References (36)
Influence of physical activity on the cellular immune system: mechanisms of action
Int.J.Sports Med.12, suppl
(1991)- et al.
Immune changes in HIV-1 infection: Significant correlations and differences in serum markers and lymphoid phenotypic antigens
Clin.Immunol.Immunopathol
(1992) - et al.
Lymphocyte interactions with endothelial cells
Immunol.Today
(1992) - et al.
Circulating ICAM-1 isoforms: diagnostic prospects for inflammatory and immune disorders
Lancet
(1991) - et al.
Selective induction of mononuclear phagocytes to produce neopterin by interferons
Immunobiol
(1988) - et al.
Neopterin as a marker for activation of cellular immunity: immunologic basis and clinical application
Adv Clin Chem
(1989) - et al.
Interferon gamma induces cell surface expression for both types of tumor necrosis factor receptors
FEBS Lett
(1992) - et al.
Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation
Immunol.Lett
(1989) Overtraining increases susceptibility to infection
Int.J.Sports Med.12, suppl
(1991)- et al.
Ultramarathon running and upper respiratory tract infections
An epidemiological survey.S.Afr.Med.J
(1983)
Infectious episodes in runners before and after Los Angeles Marathon
Med.Sci.Sports.Exerc.
Sports and allergy
Int.J.Sports Med.12, suppl
Exercise and asthma
N.Engl.J.Med
Changes in the population of lymphoid cells in human peripheral blood following physical exercise
Clin.Exp.Immunol
Effect of physical exercise on blood mononuclear cell subpopulations and in vitro proliferative responses
Scand.J.Immunol
The effect of acute exercise on natural killer cell activity of trained and sedentary human subjects
J.Clin.Immunol
The effect of exercise on secretory and natural immunity
Adv.Exp.Med.Biol
Immune parameters in athletes before and after strenuous exercise
J.Clin.Immunol
Cited by (51)
Pterins as diagnostic markers of exercise-induced stress: a systematic review
2020, Journal of Science and Medicine in SportCitation Excerpt :Neopterin concentrations showed quite a variable response in the longitudinal time points post-exercise. Tilz et al.30 measured sustained plasma neopterin up to 36 h post-mountain hiking while Castell et al.31 measured an increase within 5–15 min returning to baseline within an hour. Collectively, the systematic review reveals high-intensity running causes an immediate increase in neopterin with variable responses up to 120 h post-exercise.
Tumor necrosis factor-alpha and soluble TNF-alpha receptor responses in young vs. middle-aged males following eccentric exercise
2017, Experimental GerontologyCitation Excerpt :However, this finding is in contrast to previous research noting significant elevations in STNFR1 following prolonged endurance exercise (Ostrowski et al., 1999; Tilz et al., 1993). Ostrowski et al. (1999) and Tilz et al. (1993) observed significant changes in circulating STNFRs following both a marathon and a hiking tour, respectively. Thus, it appears that the STNFR1 response to resistance exercise may differ from that of prolonged endurance exercise.
Beyond muscles: The untapped potential of creatine
2016, International ImmunopharmacologyRole of physical activity and diet on mood, behavior, and cognition
2015, Neurology Psychiatry and Brain ResearchCitation Excerpt :The study by Agudela et al. demonstrates that skeletal muscle PGC-1α1 overexpression can counteract depression and acts as an exercise-mimetic that modulates paracrine factors and this may open up avenues to new therapeutic approaches (Moon & van Praag, 2014). Physical exercise was also observed to affect metabolism of pteridine derivatives such as neopterin and 5,6,7,8-tetrahydobiopterin (BH4) (Tilz et al., 1993). Neopterin represents a sensitive indicator of macrophage activation and oxidative stress in humans (Murr et al., 1999) and BH4 is necessary cofactor of several aromatic amino acid monooxygenases such as tryptophan 5-hydroxylase that is primary in the biosynthesis of serotonin, as well as phenylalanine and tyrosine hydroxylases that comprise the first enzymatic steps in the biosynthesis of dihydroxyphenylalanine (DOPA), adrenalin and noradrenalin and also of NO. synthases (Werner-Felmayer, Golderer, & Werner, 2002).
- a
Dr.Dietmar Fuchs, Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Fritz-Pregl-Str.3, A-6020 Innsbruck, Austria
- *
Dr.Diez-Ruiz, Department of Internal Medicine, University Hospital of Grenade, Spain, is supported by «Fondo de Investigaciones Sanitarias», Spanish Ministry of Health and Comume.