Letter to the Editor
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Cited by (10)
Analysis of patient outcomes following proton radiation therapy for retinoblastoma
2017, Advances in Radiation OncologyCitation Excerpt :Radiation therapy (RT) has a long history of use in RB treatment; for many decades, RT was the only available eye-sparing treatment modality.3-5 Although RT has been associated with high rates of disease control and vision preservation in many settings, concerns about RT-related toxicities (eg, growth abnormalities, secondary malignancies) have led to an increased use of systemic or intra-arterial chemotherapy and focal therapies (eg, cryoablation, laser photocoagulation), especially for the treatment of early stage tumors.6-9 Proton radiation therapy (PRT) is a unique form of RT that has been used to treat RB at our institution for nearly 30 years.
Risk factors for cataract after palladium-103 ophthalmic plaque radiation therapy
2011, International Journal of Radiation Oncology Biology PhysicsCitation Excerpt :In that cataracts most commonly occur in the elderly, studies on children with retinoblastoma are particularly telling (23). Schipper et al. (24, 25) delivered 45 Gy to the retina in 15 fractions in 5 weeks to 73 eyes of 39 children with retinoblastoma. Cataracts developed in 18 eyes (in which more than 1 mm of the posterior lens was included in the field).
Radiation Therapy for Orbital Tumors: Concepts, Current Use, and Ophthalmic Radiation Side Effects
2009, Survey of OphthalmologyCitation Excerpt :For example, whereas orbital bones, muscle, and fat can tolerate relatively high doses; the lens, eyelashes, retina, and lacrimal system are more radiosensitive.217 Side effects such as dry eye, eyelash loss, cataract, neovascular glaucoma, radiation retinopathy, and optic neuropathy are all potential local complications of orbital irradiation. 8,58,162,210,222 Therefore, although tumor control is the primary goal, treatment plans (dose volumes) are shaped to avoid the retina, lacrimal system, and natural lens (to decrease side effects).
Current and emerging therapy for improving outcomes in patients with intraocular retinoblastoma
2015, Expert Opinion on Orphan DrugsRadiation therapy for orbital tumors
2015, Orbital Tumors: Diagnosis and Treatment, Second EditionOcular complications of cancer therapy: A primer for the ophthalmologist treating cancer patients
2009, Current Opinion in Ophthalmology