Quantification of posterior capsule opacification with round and sharp edge intraocular lenses☆
Section snippets
Image analysis system
The computerized system by Tetz and Nimsgern7 (EPCO) is an established system that has been used for PCO research in several studies.14, 15, 22, 23, 24, 25 With this system, standardized retroillumination slit-lamp photographs are digitized and imported into the program. A detailed description of the retroillumination photographs and camera settings is given in a previous publication by Tetz et al.14
In the EPCO program the desired area of evaluation (e.g., the IOL optic area) is first marked,
Patients
At present, our PCO database consists of approximately 1000 patients. Standardized retroillumination photographs have been analyzed for all patients using the EPCO software. Posterior capsule opacification values were stored in a database together with clinical information. The data analyzed in this study were taken from this database.
Statistical analysis
Statistical evaluation included the use of frequency distribution diagrams, the analysis of variance test, and nonparametric statistical tests, such as the Kruskal-Wallis test and the Spearman correlation using the programs MS Ecxel 2000, SYSTAT 5.03 for Windows, and STATISTICA 4.5 for Windows.
Part I
The PCO values of the entire optic were for the Corneal ACR6, 1.93 ± 0.62; PMMA, 0.64 ± 0.63; AR40, 0.55 ± 0.28; Alcon Acrysof, 0.145 ± 0.27; and 0.161 ± 0.181 for the Pharmacia 911A IOL (P < 0.01, Kruskal-Wallis test; Fig 4).
The PCO values of the central 3-mm optic zone were for the Corneal ACR6, 1.64 ± 0.96; PMMA, 0.49 ± 0.39; AR40, 0.22 ± 0.32; Alcon Acrysof, 0.08 ± 0.21; and 0.06 ± 0.11 for the Pharmacia 911A IOL (P < 0.01, Kruskal-Wallis test; Fig 5).
The two IOL types with sharp-edge
Discussion
Fifty years ago, it had already been shown that the implantation of an IOL into the capsular bag after extracapsular cataract surgery reduced the incidence and amount of PCO compared with aphakic eyes or eyes with sulcus fixation of an IOL.1, 2, 3, 4, 7, 8, 9, 10, 16, 26, 27 The pressure of the optic against the posterior capsule creates a barrier effect that reduces PCO. However, PCO rates still remained around 30% to 50% in the 1980s and early 1990s.5
A biconvex IOL optic has been shown to
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Manuscript no. 210505.
The authors have no propriety interest in any products mentioned in this article.