Elsevier

The Lancet

Volume 304, Issue 7882, 21 September 1974, Pages 695-696
The Lancet

Preliminary Communications
LOCALISATION OF DEEP-VENOUS THROMBOSIS USING TECHNETIUM-99m-LABELLED UROKINASE

https://doi.org/10.1016/S0140-6736(74)93267-XGet rights and content

Abstract

99mTc (technetium)-labelled urokinase has been used to detect and localise venous thrombosis in the lower limbs. In twenty-two patients the results correlated well with those of venography. It is suggested that this method will detect both formed and forming thrombi, in contrast to the 125I-labelled fibrinogen method which will only efficiently detect actively forming thrombi. Radioisotope scanning with 99mTc-labelled urokinase can be completed within 1 hour of injection and gives good visualisation of the calf, femoral, and ileofemoral segments.

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