ORIGINAL ARTICLESPOST-EXERCISE KETOSIS
References (21)
- et al.
Lancet
(1969) - et al.
Life Sci.
(1962) - et al.
Lancet
(1963) - et al.
Proc. R. Soc. B
(1936) - et al.
Q. J. exp. Physiol.
(1958) - et al.
Klin. Wschr.
(1939) - et al.
J. Lab. clin. Med.
(1963) Ann. N.Y. Acad. Sci.
(1965)- et al.
J. clin. Invest.
(1966) - et al.
Diabetologia
(1969)
Cited by (25)
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics
2017, Cell MetabolismCitation Excerpt :Ketone body oxidation becomes a significant contributor to overall energy mammalian metabolism within extrahepatic tissues in myriad physiological states, including fasting, starvation, the neonatal period, post-exercise, pregnancy, and adherence to low-carbohydrate diets. Circulating total ketone body concentrations in healthy adult humans normally exhibit circadian oscillations between approximately 100 and 250 μM, rise to ∼1 mM after prolonged exercise or 24 hr of fasting, and can accumulate to as high as 20 mM in pathological states like diabetic ketoacidosis (Cahill, 2006; Johnson et al., 1969b; Koeslag et al., 1980; Robinson and Williamson, 1980; Wildenhoff et al., 1974). The human liver produces up to 300 g of ketone bodies per day (Balasse and Féry, 1989), which contribute between 5% and 20% of total energy expenditure in fed, fasted, and starved states (Balasse et al., 1978; Cox et al., 2016).
Ketone Body Metabolism in the Neonate
2017, Fetal and Neonatal Physiology, 2-Volume SetKetosis may promote brain macroautophagy by activating Sirt1 and hypoxia-inducible factor-1
2015, Medical HypothesesCitation Excerpt :This can be expected to promote depletion of hepatic glycogen stores while simultaneously promoting adipocyte lipolysis and hence providing the liver with more substrate for ketogenesis. Although blood ketone levels don’t notably rise during exercise – owing to rapid muscle oxidation of ketone bodies – a post-exercise rise in blood ketones has often been reported (“post-exercise ketosis”) [173,174]. Continuing carbohydrate avoidance following exercise, coupled with administration of the supplements described above, might represent a practical strategy for enabling significant ketosis to be achieved in the context of less than 24 h of carb restriction – for example, with the “mini-fast with exercise” strategy for achieving and maintaining leanness [175,176].
Lipids and Ketones
2008, Clinical Biochemistry of Domestic Animals, Sixth EditionThe nicotinic acid receptor GPR109A (HM74A or PUMA-G) as a new therapeutic target
2006, Trends in Pharmacological SciencesCarbohydrate metabolism and its regulatory hormones in anorexia nervosa
1996, Psychiatry Research