Letters to the EditorNMR IMAGING/SPECTROSCOPY SYSTEM TO STUDY BOTH ANATOMY AND METABOLISM
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Cited by (74)
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure
2021, Journal of Molecular and Cellular CardiologyCitation Excerpt :Some studies suggest that cardiac energetics is only impaired during advanced stages of HF (ATP <30–40%) with ATP levels maintained during the initial stages of metabolic remodelling [46–50]. Nevertheless, series of seminal in vivo 31P NMRs studies [26,51–54] have helped to identify the reduction of the myocardial energy reserve defined as phosphocreatine-to-ATP ratio (PCr/ATP of <1.6) led to 44% increase in death from cardiovascular causes vs 5% of DCM patients with a PCr/ATP of >1.6. Collectively, these pioneering 31P NMRS studies helped to establish cardiac energetics as a powerful and reliable prognostic indicator in HF [55].
Imaging at ultrahigh magnetic fields: History, challenges, and solutions
2018, NeuroImageCitation Excerpt :Presumably, this was dictated by the difficulty and the expense of building magnets large enough to accommodate the human body at higher magnetic fields as well as early theoretical considerations suggesting that, in the electrically lossy and conductive human body, the “frequency of operation of the spectrometer with human samples should be less than about 10 MHz [∼0.24 T]” (Hoult and Lauterbur, 1979) because of sensitivity and penetration problems predicted in the modeling. However, in 1983, the feasibility of MRI of the human head at 1.5 T (64 MHz 1H frequency) was demonstrated (Bottomley et al., 1983; Hart et al., 1983) and, rapidly, the use of 1.5 T (1.5 T) became pervasive as a clinical diagnostic instrument. This development established 1.5 T as the “high field” in MRI at the time.
Sex differences in alcohol-related neurobehavioral consequences
2014, Handbook of Clinical NeurologyBasis of Magnetic Resonance
2013, Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical ApplicationsMolecular aspects of magnetic resonance imaging and spectroscopy
1999, Molecular Aspects of MedicineThe rise of human in vivo NMR spectroscopy
1997, Solid State Nuclear Magnetic Resonance