Biochemical and Biophysical Research Communications
Volume 151, Issue 2, 15 March 1988, Pages 725-729
Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II
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Microarray analysis of gene expression in eastern oyster (Crassostrea virginica) reveals a novel combination of antimicrobial and oxidative stress host responses after dermo (Perkinsus marinus) challenge
2010, Fish and Shellfish ImmunologyCitation Excerpt :MT gene activation induced by oxygen radicals has been observed [52,53], which may explain the possible involvement of MT in the cellular anti-oxidant defense system. First, MT shows a remarkable in vitro scavenging activity against different free-radical species [54,55]; second, the cellular level of MT can be elevated by different oxidants [20,56]; third, over expression of MT can help the cultured cells resist oxidative stress [57], whereas MT-deficient cells are more sensitive to oxidizing agents and oxidative stress [58]; and fourth, MTs were also able to prevent free-radical injury to biological structures both in vitro [59] and in vivo [60]. Oxidative stress is known to induce apoptosis in many cellular systems [16].
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1993, Free Radical Biology and MedicineMetallothionein is a crucial protective factor against Helicobacter pylori-induced gastric erosive lesions in a mouse model
2008, American Journal of Physiology - Gastrointestinal and Liver Physiology
Copyright © 1988 Published by Elsevier Inc.