Congestive Heart FailureComparison of frequencies of left ventricular systolic and diastolic heart failure in chinese living in Hong Kong
Section snippets
Methods
The Prince of Wales Hospital is a major teaching and district hospital serving a community of 1.5 million people. At the time of this study there was no other fully functional acute hospitals in this area, and community care was minimal. It is therefore likely that all patients who developed clinically significant heart failure were referred to this hospital. Therefore, we prospectively studied all patients admitted over a 9-month period with the clinical diagnosis of heart failure. The records
Results
Fifteen patients (12.5%) of the total population had chronic rheumatic heart disease or significant valvular heart disease of at least moderate severity. Of the remaining 175 patients studied, 132 patients had a LVEF of ≥45% (75%). Therefore, 66% of patients with a clinical diagnosis of heart failure had a normal LVEF (the normal systolic LV failure group) compared with the systolic LV failure group in which there was impaired LV function.
Discussion
This study suggests that heart failure with normal LV systolic function or diastolic heart failure is more common than systolic heart failure in Hong Kong Chinese patients with the typical symptoms and signs of heart failure. In part this may be explained by the greater age of our patients at the time of presentation. A lower estimate of prevalence (13%) was found in the Veterans Administration Heart Failure Trial, where the average age was 59 years, and the higher estimates (about 60%) came
Acknowledgements
We are grateful to K.K. Wong, MPhil, from the Centre for Clinical Trials and Epidemiological Research, Chinese University of Hong Kong, for his statistical advice and helpful assistance.
References (11)
- et al.
The natural history of isolated left ventricular diastolic dysfunction
Am J Med
(1992) - et al.
Echocardiographic assessment of left ventricular hypertrophy:comparison to necropsy findings
Am J Cardiol
(1986) - et al.
Prevalence, clinical feature and prognosis of diastolic heart failurean epidemiologic prospective
J Am Coll Cardiol
(1995) - et al.
The aetiology of heart failure in the Chinese population of Hong Kong—a prospective study of 730 consecutive patients
Int J Cardiol
(1995) - et al.
The definition of heart failure
Eur Heart J
(1983)
Cited by (85)
Myths and facts about heart failure with preserved ejection fraction: Risk factors, longevity, potential pharmacological and exercise interventions
2013, International Journal of GerontologyCitation Excerpt :In contrast to SHF or HF with reduced ejection fraction, HFpEF patients tend to be elderly females with a history5 of hypertension8 compared to the ischemic etiology that predominates in SHF. Fig. 1 summarizes the data on risk factors from previous registries41–47 in population-based cohorts8,9,15,48–51 and randomized studies26–28,52–55. In addition, cardiovascular risk factors are also highly linked to HFpEF in large-scaled studies; this includes obesity, diabetes, and hyperlipidemia44.
Noninvasive Prediction of Left Ventricular End-Diastolic Pressure in Patients With Coronary Artery Disease and Preserved Ejection Fraction
2012, Canadian Journal of CardiologyA novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensive rats
2011, European Journal of PharmacologyHeart Failure in Developing Countries
2011, Heart FailureClinical characteristics and predictors of in-hospital mortality in acute heart failure with preserved left ventricular ejection fraction
2011, American Journal of Cardiology