AgF/TFA-promoted highly efficient synthesis of α-haloketones from haloalkynes

doi:10.1016/j.tetlet.2014.01.027

Tetrahedron Letters

Volume 55, Issue 7, 12 February 2014, Pages 1373-1375

https://doi.org/10.1016/j.tetlet.2014.01.027 Get rights and content

Abstract

A AgF/TFA-promoted highly efficient synthesis of a wide range of α-haloketones from haloalkynes is described. The reactions are conducted under convenient conditions and provide products in moderate to excellent yields, with broad substrate scope, including a variety of aromatic chloroalkynes and bromoalkynes.

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Acknowledgements

The authors thank the NSFC (21202023 and 21162001), NSF of Jiangxi Province (20114BAB213006) for financial support.

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AgF/TFA-promoted highly efficient synthesis of α-haloketones from haloalkynes

Abstract

Graphical abstract

Section snippets

Acknowledgements

Tetrahedron Lett.

J. Org. Chem.

J. Org. Chem.

Synth. Commun.

Synth. Commun.

Bull. Korean Chem. Soc.

Synthesis

Molecules

Org. Synth. Coll. III

J. Org. Chem.

Bull. Korean Chem. Soc.

Tetrahedron Lett.

Tetrahedron

J. Org. Chem.

J. Org. Chem.

Org. Lett.

Org. Lett.

J. Am. Chem. Soc.

J. Org. Chem.

J. Org. Chem.