Chapter 4 - Polymeric Materials for 3D Bioprinting

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Abstract

Three-dimensional (3D) bioprinting has emerged from the original 3D printing technology, and it aids in in vitro designing of several tissues for organ growth by retaining its original structural and functional properties. The scarcity in organ donation and difficulty in modifying existing properties of the natural organs have led to the growth of this technology. They are essential for the synthesis of organs, tissue scaffolds, testing of drugs, disease screening, etc. These 3D bioprinters utilize “bioink,” which contains specific cells required for organ synthesis dissolved in a gel or matrix. Several polymeric materials are used as the constituents of bioink, which may include either natural or synthetic polymers. The resemblance of the natural polymers with the extracellular matrix is high, because of which they yield good bioactivity; whereas, the synthetic polymers increase the mechanical integrity in bioprinting and eliminate the manufacturing limitations. Thus, this chapter delivers the significant role of various synthetic polymers and their applications in 3D bioprinting technology.

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