Differential effects of aging and disease on trabecular and compact bone density of the radius

doi:10.1016/8756-3282(91)90007-6

Bone

Volume 12, Issue 2, 1991, Pages 99-105

https://doi.org/10.1016/8756-3282(91)90007-6 Get rights and content

Abstract

We constructed a special purpose CT system to get a spatial resolution of 0.2 mm and developed a procedure for the precise determination of trabecular and compact bone density (TBD and CBD) in the radius. Seven groups of healthy females and patients were measured to explore differential effects on compact and trabecular bone. In healthy females CBD remains constant within 0.2% from age 20 to 70. TBD measured in the same individuals is reduced by 50%. The scatter of the individual CBD values is 1.5% only, that of TBD 20%. Longitudinal examinations of corticosteroid treated asthmatics during one year showed a loss of TBD of 4.8%. During the same period CBD remained completely stable. In other diseases such as hyperparathyroidism CBD is reduced as well. This study showed the feasibility of a noninvasive determination of the density of compact bone and demonstrated that density loss of compact and trabecular bone is considerably different.

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¹: Institut für Biomedizinische Technik, Moussonstrasse 18, CH-8044 Zürich, Switzerland.

²: Orthopädische Universitätsklinik Balgrist, Forchstrasse 340, CH-8008 Zürich, Switzerland.

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Original articleDifferential effects of aging and disease on trabecular and compact bone density of the radius

Abstract

Precise measurement of vertebral mineral content using computed tomography

J. Comput. Assist. Tomogr.

Quantitative Analyse von Knochenstrukturen aus Computertomogrammen von gelenknahen Skelettabschnitten

Quantitative measurement of bone density using gamma-ray computed tomography

J. Comput. Assist. Tomogr.

Performance evaluation of density measurements of axial and peripheral bone with X-ray and gamma-ray computed tomography

Phys. Med. Biol.

Normal values for trabecular and cortical bone in the radius measured by computed tomography

Clin. Phys. Meas.

Precision of measurement of bone density with a special purpose computed tomography scanner

Br. J. Radiol.

Composition of trabecular and cortical bone

Anat. Rec.

Vertebral bone mineral analysis: An integrated approach with CT

Radiology

Reference values for spongious and cortical bone mineral in single and dual energy quantitative computed tomography

Eur. J. Radiol.

Cortical bone senescence and mineral density of the humerus

Calcif. Tiss. Int.

Nuclear medicine and densitometry

Original article
Differential effects of aging and disease on trabecular and compact bone density of the radius