Neuron
ArticleBDNF in the development of the visual system of Xenopus
References (71)
- et al.
Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB
Neuron
(1991) - et al.
Expression of NGF receptor and NGF receptor mRNA in the developing and adult rat retina
Exp. Neurol.
(1991) - et al.
Nerve growth factor (NGF), proNGF and NGF receptorlike immunoreactivity in BB rat retina
Brain Res.
(1990) Neurotrophin receptors: a window into neuronal differentiation
Neuron
(1992)Fiber optic mapping of the Xenopus visual system: shift in the retinotectal projection during development
Dev. Biol.
(1983)- et al.
TrkB mediates BDNF/NT-3-dependent survival and proliferation of fibroblasts lacking the low affinity NGF receptor
Cell
(1991) - et al.
In vitro growth properties of Xenopus retinal neurons undergo developmental modulation
Dev. Biol.
(1989) - et al.
Cellular determination in the Xenopus retina is independent of lineage and birth date
Neuron
(1988) - et al.
Comparison of mammalian, chicken and Xenopus brain-derived neurotrophic factor coding sequences
FEBS Lett.
(1991) Cessation of DNA synthesis in retinal ganglion cells correlated with the time of specification of their central connections
Dev. Biol.
(1968)
The trkB tyrosine kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain
Cell
The trkB tyrosine protein kinase is a receptor for brain derived neurotrophic factor and neurotrophin-3
Cell
The trkB tyrosine protein kinase is a receptor for neurotrophin-0
Neuron
trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
Cell
Expression of NGF and NGF receptor mRNAs in the developing brain: evidence for local delivery and action of NGF
Exp. Neurol.
Dynamic aspects of retinotectal map formation as revealed by a vital-dye fiber-tracing technique
Dev. Biol.
Dynamic changes in optic fiber terminal arbors lead to retinotopic map formation: an in vivo confocal microscopic study
Neuron
The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age
Dev. Biol.
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
Neuron
Primary structure and biological activity of a novel human neurotrophic factor
Neuron
Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
Neuron
Impulse activity and the patterning of connections during CNS development
Neuron
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligand of the trkB tyrosine kinase receptor
Cell
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophic-3 but not nerve growth factor
Cell
Simple and efficient non-isotopic in situ hybridization procedure to sectioned material
Trends Genet.
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
Neuron
Retinal ganglion cell response to axotomy and nerve growth factor in the regenerating visual system of the newt (Notophtalmus viriescens): an ultrastuctural morphometric analysis
Brain Res.
Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina
Dev. Biol.
The expression, localization and functional significance of β-nerve growth factor in the central nervous system
Brain Res. Rev.
Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival
Neuron
Effect of nerve growth factor on regeneration of goldfish optic axons
Brain Res.
Purification of a new neurotrophic factor from mammalian brain
EMBO J.
Patterns of cell proliferation in the retina of the clawed frog during development
J. Comp. Neurol.
Effect of NGF on the suvival of rat retinal ganglion-cells following optic-nerve section
J. Neurosci.
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Biochemistry
Cited by (141)
Early development and function of the Xenopus tadpole retinotectal circuit
2016, Current Opinion in NeurobiologyIntraocular BDNF promotes ectopic branching, alters motility and stimulates abnormal collaterals in regenerating optic fibers
2015, Brain ResearchCitation Excerpt :To do this, we used the retinotectal system of the adult goldfish because its optic axons can regenerate after axotomy and can reform accurate and functional connections with the optic tectum, their major projection site. Also, developmental studies have shown that BDNF and its receptor trkB are present in the visual system of lower vertebrates (Cohen-Cory and Fraser, 1994; Marshak et al., 2007) like they are in mammals (Cabelli et al., 1995; Isenmann et al., 1999; Marler et al., 2014) and play similar roles in regulating growth and branching, making this a valid model to investigate the effects of BDNF. In this study, the optic nerve of the goldfish was crushed and BDNF was chronically administered to the retinal ganglion cells during optic nerve regeneration.
Retinal ganglion cell apoptotic pathway in glaucoma: Initiating and downstream mechanisms
2015, Progress in Brain ResearchCitation Excerpt :Reduction in retrograde axonal transport of neurotrophic factors, such as BDNF, from the brain to the RGC in the retina has been suggested as a critical factor underlying RGC loss and optic nerve degeneration in glaucoma (Almasieh et al., 2012) (Fig. 1). BDNF is not only delivered retrogradely from the brain but within the retina as well, and it is produced by cells in the ganglion cell layer (GCL) and the inner nuclear layer (Cohen-Cory and Fraser, 1994; Perez and Caminos, 1995). Retinal BDNF levels increase after optic nerve axotomy (Gao et al., 1997) as well as in experimental glaucoma (Guo et al., 2011; Rudzinski et al., 2004) In addition, there is early increase in BDNF mRNA levels early after ocular hypertension (Wang et al., 2010).
The molecular basis of retinal ganglion cell death in glaucoma
2012, Progress in Retinal and Eye Research