Genetic relatedness of human DNA polymerase β and terminal deoxynucleotidyltransferase
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Cited by (22)
Joining of DNA ends bearing non-matching 3′-overhangs
2002, DNA RepairCitation Excerpt :Thus, the finding that an increase in the intracellular dATP pool lead to more A–T insertions at recombination junctions during V(D)J recombination was interpreted in this way [27]. On the other hand, TdT is homologous to DNA polymerase β [28,29] and the recent discovery of DNA polymerase μ with intrinsic TdT activity may make a distinction between these two enzymatic activities problematic [30]. In a previous study we reported that the joining between and end with 3′-overhang and end with 5′-overhang was strongly reduced in a Ku-depleted egg extract [19].
Terminal deoxynucleotidyl transferasecatalysis of DNA (oligodeoxynucleotide) phosphorylation
2000, Pharmacology and TherapeuticsThe E249K mutator mutant of DNA polymerase β extends mispaired termini
1999, Journal of Biological Chemistry
Copyright © 1987 Published by Elsevier B.V.