Heterologous helminth induced resistance to Ascaris suum in guinea pigs

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Abstract

The protection inducing capacity of Toxocara canis, Ancylostoma caninum, Haemonchus contortus, Caenorhabditis briggsae and Turbatrix aceti given via the mesenteric vein to a challenge infection with Ascaris suum was evaluated. Embryonated eggs and second stage larvae of T. canis and infective larvae of A. caninum were able to induce a statistically significant level of protective immunity, while the other non-related helminths were unable to protect against a challenge infection.

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