Effects of calcium and magnesium acetates on tissue distribution of carcinogenic doses of cadmium chloride in wistar rats
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Effects of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats
2003, Food and Chemical ToxicologyCitation Excerpt :Several studies have shown that cadmium can compete with calcium at the pituitary level (Waalkies and Poirier, 1984; Milos et al., 1989), which results in altered calcium regulation. Thus it either interferes with calcium influx through the membrane channel (Poirier et al., 1983; Kasprzak and Poirier, 1985; Cooper et al., 1987) or alters intracellular calcium mobilization. The results of our study agree with this hypothesis as both LH and FSH levels were decreased on cadmium accumulation.
Pubertal and postpubertal cadmium exposure differentially affects the hypothalamic-pituitary-testicular axis function in the rat
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