Trends in Genetics
ReviewAt the heart of the budding yeast cell cycle
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Cited by (298)
Inferring cell cycle phases from a partially temporal network of protein interactions
2023, Cell Reports MethodsMitotic kinase oscillation governs the latching of cell cycle switches
2022, Current BiologyInvestigating molecular crowding during cell division and hyperosmotic stress in budding yeast with FRET
2021, Current Topics in MembranesCell-cycle involvement in autophagy and apoptosis in yeast
2017, Mechanisms of Ageing and DevelopmentCitation Excerpt :Its regulation is essential for the orderly and timely progression of the cell-cycle phases (Hartwell and Weinert, 1989). This is mainly dependent on a highly varied molecular set containing important regulatory motifs which are tightly regulated by complex transcriptional controls mainly at the G1-S and G2-M stages of the cell cycle (Glotzer et al., 1991; Kaizu et al., 2010; Mendenhall and Hodge, 1998; Nasmyth, 1996; Pines, 1999). Cyclin-dependent kinases (CDKs) are a group of serine-threonine protein kinases essential in controlling the alternation between DNA synthesis and DNA segregation during the cell cycle (Kaizu et al., 2010).
Transmembrane signaling in Saccharomyces cerevisiae as a model for signaling in metazoans: State of the art after 25years
2014, Cellular SignallingCitation Excerpt :Since the discovery of enzymes, namely, fermentation of sugar in cell free extract of yeast cells at the end of the 19th century [1] (enzyme = in yeast), many of the metabolic and catabolic processes of the eukaryotic cell have been revealed in this organism [2–5]. Baker's yeast continued to serve as a central model organism in the last quarter of the 20th century and contributed to the understanding of critical processes such as replication and repair [6,7], cell cycle [8,9], transcription and chromatin remodeling [10–12], protein synthesis and degradation [13–15], transport, trafficking and protein sorting [16,17], meiosis and recombination [18–21], and even the mechanism of action of oncoproteins [22–27]. Yeast became an attractive model, not only because many of its biochemical machineries are similar to those of multicellular organisms [4,13,17,28–33], but also because it is unusually amenable to experimental manipulation [34–41].