Elsevier

Neuroscience Research

Volume 23, Issue 3, October 1995, Pages 317-319
Neuroscience Research

Rapid communication
Water deprivation in the rat induces nitric oxide synthase (NOS) gene expression in the hypothalamic paraventricular and supraoptic nuclei

https://doi.org/10.1016/0168-0102(95)00956-6Get rights and content

Abstract

We examined the effects of water deprivation on nitric oxide synthase (NOS) gene expression in the rat hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), using in situ hybridization histochemistry. Dehydration caused a significant increase in NOS gene transcripts in the PVN and SON but not in the subfornical organ (SFO). The results suggest that dehydration has a major effect on the NOS gene expression in the PVN and SON.

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Present address: School of Biological and Chemical Sciences, University of Greenwich, London SE18 6TF, UK

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