The impact of surgical and pathological findings on radiotherapy of early breast cancer
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Intraoperative evaluation of surgical margins in breast conserving therapy
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2009, The Breast: Comprehensive Management of Benign and Malignant DiseasesBasal cell-like (triple-negative) breast cancer, a predictor of distant metastasis in African American women
2008, American Journal of SurgeryCitation Excerpt :Mirza et al [21] found independent predictors of increased risk of locoregional recurrence to be young age, positive lymph nodes, and large tumor size. Borger et al [22] in a literature review observed that there is no agreement on prognostic factors for locoregional recurrence. Risk factors reported for distant metastasis include mitotic index, nodal status, and tumor size.
Quantitative molecular diagnosis of axillary drainage fluid for prediction of locoregional failure in patients with one to three positive axillary nodes after mastectomy without adjuvant radiotherapy
2006, International Journal of Radiation Oncology Biology PhysicsPatterns of care in radiotherapy of breast cancer in Austria 1985: Data acquisition and comparison with data of US-PCS 1983
2004, Radiotherapy and OncologyCitation Excerpt :Evaluating the quality of radiotherapy was the principal purpose of both studies, however, surgical and histopathological parameters and systemic therapy were also considered. Without doubt, optimal breast cancer treatment can be achieved only through good co-operation between many disciplines, i.e. surgery, pathology, internal medicine and radiotherapy [2,10,15]. Median age of patients was nearly identical in both studies, but there were slightly more pre-menopausal patients in the US-PCS83 (22% vs. 33%).
Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy
2002, American Journal of SurgeryCitation Excerpt :Thus, while specimen slice radiography cannot guarantee negative margins, it does assist the surgeon intraoperatively in obtaining more tissue if the initial margin appears radiographically close. Table 1presents a representative sample of the available studies examining the relationship between surgical margin and LR in invasive ductal carcinoma (IDC) [19,28–60]. In the largest group of studies (shown as “+ versus −” in Table 1), negative margins are not defined quantitatively.