Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Studies on the complex formed between bacitracin A and divalent cations
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Cited by (10)
Peptide antibiotic and actin-binding protein as mixed-type inhibitors of Clostridium difficile CDT toxin activities
2005, Biochemical and Biophysical Research CommunicationsCitation Excerpt :Another cyclic peptide, bacitracin, was preventive. It binds divalent metal ions like Zn2+ through its His10 imidazole ring and Mn2+ via the thiazoline ring for its biological activity [31], making contention for metal ions seems imminent. Bacitracin has high reactivity with biomolecules like nucleotides, proteins, lipids, and receptors [32].
Metal binding and structure-activity relationship of the metalloantibiotic peptide bacitracin
2002, Journal of Inorganic BiochemistryCitation Excerpt :The thiazoline ring was suggested to bind to Mn2+ at pH ∼6.6. Later studies [123–125] indicated that divalent metal ions such as Zn2+ were bound to bacitracin through the δ-N of the imidazole ring of His10, the sulfur atom of the thiazoline ring, and the Glu4 carboxylate. No evidence for the binding of Asp11 was found, and the participation of the Ile1 terminal amino group was not conclusive.
EXAFS study of zinc coordination in bacitracin A
1999, Biochimica et Biophysica Acta - Protein Structure and Molecular EnzymologyX-Ray structure of the antibiotic bacitracin A
1991, FEBS Letters1 Nickel
1987, Coordination Chemistry ReviewsThe chelating peptide (GPAGPHGPPG) derived from Alaska pollock skin enhances calcium, zinc and iron transport in Caco-2 cells
2017, International Journal of Food Science and Technology
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Present address: Department of Biochemistry, Indiana University School of Medicine, Indianapolis, IN 46223, U.S.A.
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Present address: Department of Biochemistry and Biophysics, Texas A & M University, College Station. TX 77843, U.S.A.