Elsevier

Regulatory Peptides

Volume 54, Issue 1, 10 November 1994, Pages 143-144
Regulatory Peptides

Isolation of cDNA clones homologous to opioid receptors

https://doi.org/10.1016/0167-0115(94)90431-6Get rights and content

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Cited by (39)

  • Opioids and their receptors: Are we there yet?

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    He subsequently proposed that the “M” receptors be named mu and the “N” termed kappa, based upon the pharmacology of ketocyclazocine (Martin et al., 1976). The third member of the opioid receptor family was proposed by Kosterlitz based upon the enkephalins and termed delta (Lord et al., 1977), followed by the closely related peptide orphanin FQ/nociceptin (Meunier et al., 1995; Reinscheid et al., 1995) and its receptor, ORL1 (also known as KOR-3) (Bunzow et al., 1994; Chen et al., 1994; Fukuda et al., 1994; Keith et al., 1994; Mollereau et al., 1994; Pan et al., 1994). Much effort has been focused upon targeting these additional receptor classes to develop analgesics lacking the problems of the traditional opiates used clinically – which are almost all mu.

  • Nociceptin orphanin FQ <inf>1-13</inf>-NH <inf>2</inf>

    2007, xPharm: The Comprehensive Pharmacology Reference
  • Nociceptin

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Supported by the W.M. Keck Foundation & NIDA DA-05010.

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