Signal transduction and ligand-binding domains of the tachykinin receptors
References (16)
- et al.
Molecular characterization of mammalian tachykinin receptors and a possible epithelial potassium channel
Rec. Prog. Horm. Res.
(1990) - et al.
Molecular characterization of rat substance K receptor and its mRNAs
Biochem. Biophys. Res. Commun.
(1989) - et al.
Molecular characterization of a functional cDNA for rat substance P receptor
J. Biol. Chem.
(1989) - et al.
Cloning and expression of a rat neuromedin K receptor cDNA
J. Biol. Chem.
(1990) - et al.
Selective inhibition of expression of the substance P receptor mRNA in pancreatic acinar AR42J cells by glucocorticoids
J. Biol. Chem.
(1990) - et al.
Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected chinese hamster ovary cells
J. Biol. Chem.
(1992) - et al.
Substance K: A novel mammalian tachykinin that differs from substance P in its pharmacological profile
Life Sci.
(1984) Mammalian tachykinin receptors
Annu. Rev. Neurosci.
(1991)
Cited by (29)
An imidazole based H-Phe-Phe-NH<inf>2</inf> peptidomimetic with anti-allodynic effect in spared nerve injury mice
2018, Bioorganic and Medicinal Chemistry LettersRoles of substance P and ATP in the subepithelial fibroblasts of rat intestinal villi
2013, International Review of Cell and Molecular BiologyCitation Excerpt :The tachykinins released act on tachykinin receptors (NK1, NK2, NK3) on the various cells (Nakanishi, 1991; Pennefather et al., 2004; Quartara and Maggi, 1997, 1998). They can interact with multiple G proteins, which couple to phospholipase C via Gq and to adenyl cyclase via Gs, and thus stimulate phosphatidylinositol hydrolysis and cyclic AMP formation, respectively (Guard and Watson, 1991; Nakajima et al., 1992; Nakanishi et al., 1993). In NK1R transfected Chinese hamster ovary (CHO) cells, SP-stimulated cAMP accumulation was high as compared with NK3R–CHO cells (Nakajima et al., 1992).
Inflammatory cells as source of tachykinin-induced mucus secretion in chronic bronchitis
2005, Regulatory PeptidesG Protein-Coupled Receptors in Invertebrates: A State of the Art
2003, International Review of CytologyCitation Excerpt :Furthermore, an increase of cyclic AMP production was observed after receptor activation with Lom-TK III. In comparison, mammalian NK receptors also elicit both types of responses (PLC and AC) in mammalian cells (Nakajima et al., 1992; Nakanishi et al., 1993). Few pharmacological data are available on the Drosophila DTKR and NKDR receptors.
Chapter VI Neurokinin receptors in the CNS
2000, Handbook of Chemical NeuroanatomySubcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors
1999, Journal of Biological Chemistry