Electroencephalographic sleep studies in depressed outpatients treated with interpersonal psychotherapy: I. Baseline studies in responders and nonresponders
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REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis
2024, Sleep Medicine ReviewsAssociations between daily affect and sleep vary by sleep assessment type: What can ambulatory EEG add to the picture?
2021, Sleep HealthCitation Excerpt :Our analyses with EEG sleep demonstrated that higher morning negative affect predicted longer REM duration that night. Longer REM duration is often a feature in clinical depression and anxiety,51 and other studies have similarly found that inducing negative affect may cause increases in subsequent REM sleep.52-54 Our other null results with EEG sleep also support findings from Konjarski et al (2018), who revealed relatively null or inconsistent results in ambulatory studies on actigraphy and affect in nonclinical samples.8,9,31
REM density is associated with treatment response in major depression: Antidepressant pharmacotherapy vs. psychotherapy
2021, Journal of Psychiatric ResearchCitation Excerpt :Besides wake EEG, the role of sleep parameters has also been investigated. A study published in 1992 from Buysse and colleagues (Buysse et al., 1992) showed that psychotherapy non-responders had longer sleep latencies, lower sleep efficiency, and increased automated measures of rapid eye movement (REM) activity at baseline than responders. In a similar study comparing depressive patients who underwent a interpersonal psychotherapy treatment program of 12–20 weeks, a study from the same group (Buysse et al., 1999) found that non-remitters had worse subjective sleep quality and more REM activity prior to treatment as compared to remitters (defined as Hamilton depression score of <7 for three consecutive weeks).
Sleep disturbances in pediatric depression
2011, Asian Journal of PsychiatryCitation Excerpt :Repetitive transcranial magnetic stimulation (rTMS) also was shown to suppress REM sleep (Cohrs et al., 1998). Baseline EEG sleep measures, such as sleep continuity measures and reduced REM latency, predicted clinical response to cognitive-behavior therapy (CBT) and interpersonal therapy (IPT) in adult patients with depression (Buysse et al., 1992b; Jarrett et al., 1990b). However, no significant changes in EEG sleep macroarchitecture occurred in response to IPT although modest changes occurred in automated measures of delta sleep activity and REM sleep activity (Buysse et al., 1992a).
Electroencephalographic sleep profiles in treatment course and long-term outcome of major depression: Association with DEX/CRH-test response
2004, Journal of Psychiatric ResearchMicrostructure of sleep in depressed patients according to the cyclic alternating pattern
2003, Journal of Affective Disorders
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Daniel J. Buysse, M.D., is Assistant Professor of Psychiatry; David J. Kupfer, M.D., is Professor and Chairman; Ellen Frank, Ph.D., is Associate Professor of Psychology and Psychiatry; Timothy H. Monk, Ph.D., is Associate Profesor of Psychiatry; Angela Ritenour, B.A.,is Research Associate; and Cindy L. Ehlers, Ph.D., is Adjunct Associate Professor in the Department of Psychiatry, University of Pittsburgh School of Medicine. Dr. Ehlers is also Associate Member, Department of Neuropharmacology, Research Institute of the Scripps Clinic.