Leaded gasoline — A cause of cancer

doi:10.1016/0160-4120(80)90154-3

Environment International

Volume 3, Issue 6, 1980, Pages 465-471

https://doi.org/10.1016/0160-4120(80)90154-3 Get rights and content

Abstract

In the course of earlier tests the authors had found that the cancer mortality among 231 adult persons living adjacent to an automobile road was much higher than among persons living in a traffic-free section of the same town. Fifty-nine of the above individuals residing adjacent to the automobile road had been treated with calcium EDTA to eliminate lead. Only one of these later died of cancer. Of the persons who were not treated with calcium EDTA, on the other hand, 30 died of cancer, or ten times more percentage-wise.

The existence of small lead deposits as well as the health-impairing effect of lead were demonstrated by measurements of lead and delta-aminolaevulinic acid in urine. After treatment with calcium EDTA, the lead content, as well as the amount of delta-aminolaevulinic acid, became normal. The concentrations of lead were found to be greater in suspended dust particles and in sediment dust along the automobile artery than elsewhere in the town.

These findings, together with many other reports in the medical literature lead to the suspicion that lead in automobile gasoline, combined with other carcinogenic substances in automotive exhaust gases, increases the incidence of cancer.

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View full text

Leaded gasoline — A cause of cancer

Abstract

Lancet

Tumor rejection in experimental animals treated with radioprotective thiols

Cancer Res.

On the behaviour of active deposit of lead in the Japanese free from occupational exposure to lead

Ind. Health

L'action d'un produit chélateur. Le calcitétracémate disodique sur l'évolution du carcinome T8 Guérin chez le rat

Rev. Path. gén.

Laboratory diagnosis of increased lead absorption

Archs. envir. Hlth.

On the kinetics of lead in the human body

J. Math. Biol.

Alveolar Macrophages: reduced number in rats after prolonged inhalation of lead sesquioxide

Science

Bleidepots bei Anwohnern einer Autostrasse

Med. Neuheiten

Nervöse Störungen durch Autoabgase

Praxis

Motorisierung — wichtigste Ursache für Krebsentstehung?

Praxis

Gesundheitsschädigung durch Bleibenzin

Praxis

Bleibenzin und Krebsmortalität

Schweiz. med. Wschr.

Polycyclic aromatic hydrocarbons in soils of a mountain valley: correlation with highway traffic and cancer incidence

Envir. Sci. Technol.

The induction of renal tumors by feeding lead acetate to rats

Br. J. Cancer

Cell proliferation in rat kidneys after prolonged treatment with lead

Am. J. Path.

Parenteral lead subacetate induced sarcomas in rats

Beeinflussung des Abbaus von Benz(a)pyren in der Lunge durch Schwermetalle

A follow-up study of lead workers

Br. J. ind. Med.

Quantitative Bestimmung von 5-Aminolävulinsäure und Porphobilinogen im Urin mit Ionenaustauschchromatographie-Fertigsäulen

Z. klin. Chem. klin. Biochem.

Chemische Noxen als Krebsursachen

Bull. Schweiz. Krebsliga

Carcinogenity of tetraethyl lead

Experientia

Chelation and cancer — a speculative review

Umwelthygiene in der Raumplanung

The Nashville air pollution study — VII. Mortality from cancer in relation to air pollution

Archs. envir. Hlth.

Blei-Vorsogeuntersuchungen und daran anschliessende Entbleiungskuren bei Sicherheitsbeamten der Bundes-Polizeidirektion Wien

Forum Umwelt-Hygiene

Luftverunreinigung und Lungenkrebs

Naturwissenschaften

Das Problem der Benzinverbleiung

Bull. Eidg. Ges.-Amt. Beilage

Occupational and Environmental Cancers of the Urinary Systems

Verhinderung der 3,4-Benzopyren-Kanzerogenese durch natürliche und synthetische Verbindungen

Münch. med. Wschr.

Editorial comment (R.L. Zielhuis)

Arch. Envir. Hlth.

Motorisierung und Krebsgefährdung

Schweiz. med. Wschr.

Effects of lead oxide on the induction of lung tumors in Syrian hamsters

J. Natn. Cancer Inst.

Lung cancer and environment

J. occup. Med.

Berufliche Bleibelastung durch Autoabgase in Grossstadtstrassen

Dt. med. Wschr.