ArticleCentral glucagon-induced hyperglycemia is mediated by combined activation of the adrenal medulla and sympathetic nerve endings
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The mechanism underlying the central glucagon-induced hyperglycemia and anorexia in chicks
2012, Comparative Biochemistry and Physiology - A Molecular and Integrative PhysiologyCitation Excerpt :Intravascular administration of glucagon temporally increased the plasma glucose concentration in rats, whereas prolonged hyperglycemia was observed when glucagon was administered centrally (Marubashi et al., 1985). Central glucagon-induced hyperglycemia was also reported in mice (Amir, 1986), dogs (Agarwala et al., 1986), sheep (Kurose et al., 2009), and chicks (Honda et al., 2007a). Since blood glucose is one of the satiety signals, it is therefore likely that glucagon-induced hyperglycemia is related to the anorexigenic action of glucagon in mammals and chicks.
Effects of intracerebroventricular injections of des-His<sup>1</sup>(Glu<sup>9</sup>) glucagon amide on the regulatory thermogenesis in muscovy ducklings
2000, Comptes Rendus de l'Academie des Sciences - Serie IIITissue-specific modulation of rat glucagon receptor mRNA by thyroid status
1998, Molecular and Cellular EndocrinologySomatostatin and the paraventricular hypothalamus: modulation of energy balance
1993, Brain ResearchGlucagon and the paraventricular hypothalamus: modulation of energy balance
1993, Brain Research
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