Oral candidiasis: Forerunner of acquired immunodeficiency syndrome (AIDS)?

doi:10.1016/0030-4220(85)90243-9

Oral Surgery, Oral Medicine, Oral Pathology

Volume 60, Issue 5, November 1985, Pages 532-534

Oral Surgery, Oral M...

https://doi.org/10.1016/0030-4220(85)90243-9 Get rights and content

Abstract

A 42-year-old man who used intravenous drugs had oral candidiasis and weight loss. Careful examination led to a diagnosis of AIDS. The patient subsequently died of disseminated cryptococcosis, systemic candidiasis, and polymicrobial bacteremia. The circumstances and progression noted in this case led to the recommendation that an aggressive screening for AIDS should be performed on patients at high risk for this syndrome who present with oralCandida infection.

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Morbid Mortal Weekly Rep
(1985)

There are more references available in the full text version of this article.

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This article describes the baseline findings from a study designed to compare the oral manifestations of HIV infection in homosexual men and intravenous drug users. Both seropositive and seronegative persons were studied. A standard examination instrument was developed to record indexes of oral disease as well as to record the presence of oral lesions. The two groups differed in terms of education, race, socioeconomic status, employment status, housing, and smoking experience. The prevalence and type of oral lesions differed in the two seropositive groups. In seropositive homosexual men, white lesions on the tongue (28.4%) predominated; whereas for the seropositive intravenous drug users, oral candidiasis (43.0%) and gingival marginal erythema (33.3%) were most often detected. We also observed that seronegative intravenous drug users displayed a greater number of oral lesions than seronegative homosexual men. For seropositive homosexual men, lesion presence was significantly associated with decreased levels of CD4; positive associations were seen with current smoking, antiviral drug use, and antibiotic use, and a negative association was observed with current employment. In contrast, only exposure to antiviral drugs was significantly correlated with lesion presence for seropositive intravenous drug users. This baseline analysis from our longitudinal study suggests clear differences in oral manifestations of HIV infection between seropositive homosexual men and intravenous drug users and between seronegative homosexual men and intravenous drug users. Among other parameters, it is apparent that lifestyle, access to health care, and the condition of the oral cavity before infection influence the development of oral lesions in persons with HIV infection.
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Short communication & case reportOral candidiasis: Forerunner of acquired immunodeficiency syndrome (AIDS)?

Abstract

Acquired immune deficiency syndrome in the United States: the first 1,000 cases

J Infect Dis

Update: Acquired immunodeficiency syndrome (AIDS) - United States

Morbid Mortal Weekly Rep

Update: Acquired immunodeficiency syndrome (AIDS) - United States

Morbid Mortal Weekly Rep

Short communication & case report
Oral candidiasis: Forerunner of acquired immunodeficiency syndrome (AIDS)?