Growth hormone and prolactin release by substance P in rats☆
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Cited by (105)
Substance P stimulates Growth Hormone (GH) and GH-Releasing Hormone (GHRH) secretions through tachykinin NK2 receptors in sheep
2012, PeptidesCitation Excerpt :Substance P has been sequenced and its structure turned out to be a peptide of 11 aminoacids [1]. The role of substance P in Growth Hormone (GH) secretion was previously shown [10,19]. Those authors showed that an i.v. injection of substance P significantly increases GH secretion in rats.
Tachykinins and the control of prolactin secretion
2006, PeptidesCitation Excerpt :With all these reservations in mind, however, it was very evident that SP induced significant prolactin release. Kato et al. [82] were also able to show that l-dopa, a precursor of dopamine, was able to completely block the stimulatory effect of SP. Furthermore, SP was also effective in inducing prolactin release in animals with extensive damage of the hypothalamus, and this suggests that SP action was exerted at the pituitary level.
Substance P increases intracellular Ca<sup>2+</sup> in individual rat pituitary lactotrophs, somatotrophs, and gonadotrophs
1997, Molecular and Cellular EndocrinologyChronic administration of neurokinin SP improves maze performance in aged Rattus norvegicus
1994, Behavioral and Neural Biology
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Supported in part by grants from the Ministry of Education, the Ministry of Welfare, the Tobacco & Salt Public Corporation, Japan.