Elsevier

Life Sciences

Volume 14, Issue 1, 1 January 1974, Pages 157-162
Life Sciences

Effects of early malnutrition on Swiss white mice: Avoidance learning after rearing in large litters

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Abstract

Mice were undernourished by rearing in litters of 20 pups per mother, weaned onto stock diet and their shuttle-box avoidance performance measured at 2 months of age. The mice from these large litters learned the avoidance response more slowly than controls (mice reared in litters of 5). In a second experiment, avoidance performance was measured after nutritional rehabilitation until 2, 4 or 6 months old. No significant improvement was observed in the previously malnourished mice. In the controls, performance was high at 2 and 4 months but by 6 months had fallen almost to the same level as the test group.

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