Research articleFibre areas and histochemical fibre types in the quadriceps muscle of paraplegic subjects
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Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies
2022, Current Opinion in PharmacologyCitation Excerpt :Sensorimotor deficits are an obvious consequences of SCI, however, the spinal cord also plays a critical role in coordinating bodily functions [3] via complex bidirectional communication between the autonomic, endocrine, and immune systems [4,5], which may also be damaged after SCI and result in widespread dysfunction in multiple organ systems [6–8]. For example, with long-term injury, physical limitations related to movement, musculoskeletal activity and weight-bearing contribute to deleterious changes in body composition, including rapid and long-term declines in metabolically active muscle-mass [9–17] and bone [18–24], and significant increases in central adiposity [25–27]. Recurrent and chronic infection in the skin attributable to pressure ulcers [28] and urinary tract infections due to bladder dysfunction and catheter use are common following spinal cord injury [29,30].
Quantifying muscle coactivation in individuals with incomplete spinal cord injury using wavelets
2020, Clinical BiomechanicsCitation Excerpt :Diminished activity and/or denervation after SCI may both contribute to changes in muscle fiber composition after SCI. Biopsy studies in individuals with complete SCI show that there is significantly higher proportion of fast-twitch muscle fibers that is evident even within a month post-injury and becomes more dominant with greater time post-injury (Burnham et al., 1997; Grimby et al., 1975; Round et al., 1993). A common method of quantifying activation is to look at the timing or amount of overlap in EMG signals of agonist-antagonist muscle pairs.
Time course of denervation-induced changes in gastrocnemius muscles of adult and old rats
2018, Experimental GerontologyTorque and mechanomyogram relationships during electrically-evoked isometric quadriceps contractions in persons with spinal cord injury
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