The effect of limb immobilization and stretch on the fine structure of the neuromuscular junction in rat muscle

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Abstract

Limb immobilization of rat plantaris muscle in the stretched position for 3 weeks led to increased postsynaptic areas of junctional folds and clefts per nerve terminals in both type I and type II muscle fibers. In addition, various ultrastructural alterations were evident in both types of end plates.

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This Research was supported by grant G008300071 from the National Institute of Handicapped Research, U.S. Department of Education, Washington D.C. The authors acknowledge the technical assistance of Ruth Johnston and Barbara Zimmer.

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