Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
Regular paperγ-Linolenic acid dietary supplementation can reverse the aging influence on rat liver microsome Δ6-desaturase activity
References (22)
- et al.
Biochem. Biophys. Res. Commun.
(1989) Med. Hypotheses
(1981)- et al.
Nutr. Res.
(1987) - et al.
J. Biol. Chem.
(1951) - et al.
J. Biol. Chem.
(1957) - et al.
Biochim. Biophys. Acta
(1976) - et al.
Prostaglandins Leukotr. EFAs
(1989) - et al.
Eur. J. Pharmacol.
(1988) - et al.
Am. J. Physiol.
(1970) - et al.
Biochem. Int.
(1988)
Ann. Nutr. Aliment.
Cited by (61)
Lipid changes in the aged brain: Effect on synaptic function and neuronal survival
2012, Progress in Lipid ResearchCitation Excerpt :Correspondingly, levels of monounsaturated fatty acids were also lowered to the same levels in the aged animals [59]. Furthermore, another desaturase, delta-6-desaturase, which is involved in the metabolism of n − 6 fatty acids has been shown to decrease with aging in rat liver [60–62]. In brain, however, a dramatic decrease was described during pre- and postnatal development up to postnatal day 21 but it remained nearly constant thereafter [61].
HIgh dietary and plasma levels of the omega-3 fatty acid docosahexaenoic acid are associated with decreased dementia risk: The rancho bernardo study
2011, Journal of Nutrition, Health and AgingEvening Primrose Oil Supplementation Increases Citraturia and Decreases Other Urinary Risk Factors for Calcium Oxalate Urolithiasis
2009, Journal of UrologyCitation Excerpt :Indeed, a significant negative correlation was reported between the dietary intake of linoleic acid (ω-6 pathway) and α-linolenic acid (ω-3 pathway), and the expression in leukocytes of the 2 desaturase genes.20 Another study showed that EPO administration restored the activity of δ-6-desaturase, which had become impaired by aging.21 A link between EFA ingestion and urinary Ox excretion was previously proposed.7
Effects of dietary fats on bone health in advanced age
2003, Prostaglandins Leukotrienes and Essential Fatty Acids