Fibrinolytic activity of oral anaerobic bacteria
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Cited by (60)
Microbiota of alveolar osteitis after permanent tooth extractions: A systematic review
2021, Journal of Stomatology, Oral and Maxillofacial SurgeryCitation Excerpt :Very few studies have focused on the etiology of AO. On one hand, some papers have reported that bacteria might induce fibrinolytic activity and lysis of the blood clot [9,12]. On the other hand, studies using next-generation sequencing (NGS) of 16S rRNA are scarce in the dental field – a fact that can result in an incomplete analysis of the implicated microbiota.
Alveolar Osteitis: A Review of Current Concepts
2020, Journal of Oral and Maxillofacial SurgeryCitation Excerpt :Immediately after extraction, a fibrin meshwork is delivered to the site via the vascular supply, which facilitates fibrin deposition and formation of the blood clot. Fibrin deposition is an important step in the healing process because it acts as a physical barrier and prevents the movement of bacteria into nearby healthy tissue.14 In contrast, fibrinolysis (destruction of the clot) occurs through the liberation of tissue kinases during the inflammation caused by the trauma of the extraction.
High-Throughput Sequencing Analysis of Microbial Profiles in the Dry Socket
2019, Journal of Oral and Maxillofacial SurgeryInitial study on facilitating wound healing after tooth extraction by using microbial fiber membrane-Flagyl
2011, Journal of Oral and Maxillofacial SurgeryClinical concepts of dry socket
2010, Journal of Oral and Maxillofacial SurgeryCitation Excerpt :In 1978, Nitzan et al45 demonstrated a possible relationship between the presence of aerobic micro-organisms and the etiology of dry socket. They also reported high fibrinolytic activity in the cultures of anaerobic Treponema denticola, which is found in periodontal disease.45 Dry socket rarely occurs during childhood, a period in which this micro-organism is usually not detected in the oral environment.
Modern concepts in understanding and management of the "dry socket" syndrome: comprehensive review of the literature
2009, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and EndodontologyCitation Excerpt :As will be discussed subsequently, antibiotics that are specific to anaerobes seem to reduce the incidence of dry socket.10 Finally T. denticola exhibits plasmin-like fibrinolytic activity while other common oral bacteria have little such innate activity25 and is a late colonizer of the mouth, which implicated it further because dry socket rarely occurs in childhood.2 No papers, however, have been able to support a direct cause-effect relationship between bacteria and dry socket.26