The role of the “indifferent” cell of the tubal epithelium

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Abstract

The “indifferent” cell of the tubal epithelium is a specific variety and is recognized by simple histologic study. By use of acridine orange fluorescence and incubation with H3-thymidine this cell appears to be metabolically more active than the commonly described varieties of the tubal epithelium. In conditions demonstrating increased proliferation of the epithelium, e.g., salpingitis, increase in metabolically active cells corresponds to the increase in the numbers of “indifferent” cells. It is postulated that this indifferent cell is the cell from which the mature epithelial cell, and possibly even the stroma, regenerates.

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Supported in part by National Institutes of Health Research Grant No. CA-05319-06 and the Nellie McCarty Research Grant.

American Cancer Society Advanced Clinical Fellow.

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