P-glycoprotein and multidrug resistance
References (65)
- et al.
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
Cell
(1993) - et al.
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
Science
(1992) Purification and reconstitution of functional human P-glycoprotein
J Bioenerg Biomembr
(1995)- et al.
The effect of ion channel blockers, immunosuppressive agents, and other drugs on the activity of the multi-drug transporter
Int J Cancer
(1993) - et al.
Reconstitution of drug transport by purified P-glycoprotein
J Biol Chem
(1995) Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domain-6 and domain-12
J Biol Chem
(1993)- et al.
Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis
Proc Natl Acad Sci USA
(1992) - et al.
Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein
J Biol Chem
(1993) - et al.
Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance
Mol Cell Biol
(1989) - et al.
Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities
J Biol Chem
(1995)
Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity
J Biol Chem
(1995)
Both P-glycoprotein nucleotide-binding sites are catalytically active
J Biol Chem
(1995)
The catalytic cycle of P-glycoprotein
FEBS Lett
(1995)
Cystic fibrosis-type mutational analysis in the ATP-binding cassette transporter signature of human P-glycoprotein MDR1
J Biol Chem
(1994)
Modulation of human P-glycoprotein ATPase activity by interaction between overlapping substrate-binding sites
Proc Am Assoc Cancer Res
(1996)
Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein
J Biol Chem
(1993)
Phorbol esters induce multidrug resistance in human breast cancer cells
Proc Natl Acad Sci USA
(1988)
Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase-C
J Biol Chem
(1993)
Phosphorylation by protein kinse C and cyclic AMP-dependent protein kinase of synthetic peptides derived from the linker region of human P-glycoprotein
Biochem J
(1994)
The cystic fibrosis transmembrane conductance regulator
Annu Rev Physiol
(1993)
Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells
J Biol Chem
(1996)
Volume-activated chloride currents associated with the multidrug resistance P-glycoprotein
J Physiol (Lond)
(1995)
Volume-sensitive chloride channel activity does not depend on endogenous P-glycoprotein
J Biol Chem
(1995)
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
Science
(1996)
Genetic analysis of the multidrug transporter
Annu Rev Genet
(1995)
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
Cell
(1986)
Cellular and biochemical aspects of multidrug resistance
P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake
Proc Natl Acad Sci USA
(1996)
Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate
Int J Cancer
(1996)
Multidrug resistance proteins and other drug transport-related resistance to natural product agents
Curr Opin Oncol
(1995)
Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells
FEBS Lett
(1996)
The role of the MDR protein in altered drug translocation across tumor cell membranes
Biochim Biophys Acta
(1995)
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