ORIGINAL ARTICLESDouble-blind study of selective decontamination of the digestive tract in intensive care
References (29)
- et al.
Pneumonia in the critically ill hospitalized patient
Chest
(1990) - et al.
Aspiration of gastric bacteria in antacid-treated patients: a frequent cause of postoperative colonisation of the airway
Lancet
(1982) - et al.
Effect of selective decontamination of the digestive tract on respiratory tract infections and mortality in the intensive care unit
Lancet
(1991) - et al.
Triple regimen of selective decontamination of the digestive tract, systemic cefotaxime, and microbiological surveillance for prevention of acquired infection in intensive care
Lancet
(1988) - et al.
Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation
Am Rev Respir Dis
(1986) - et al.
Nosocomial infection among patients in different types of intensive care units at a city hospital
Crit Care Med
(1986) - et al.
Nosocomial respiratory infections with gram-negative bacilli
Ann Intern Med
(1972) - et al.
Bacteriology of hospital-acquired pneumonia
Arch Intern Med
(1986) Sucralfate
N Engl J Med
(1991)- et al.
APACHE II: a severity of disease classification system
Crit Care Med
(1985)
Prognosis in acute organ system failure
Ann Surg
The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care
J Trauma
Age, chronic disease, sepsis, organ system failure, and mortality in a medical intensive care unit
Crit Care Med
The effect of oropharyngeal decontamination using topical non-absorbable antibiotics on the incidence of nosocomial respiratory tract infection in multiple trauma patients
J Trauma
Cited by (199)
Ventilator-Associated Tracheobronchitis
2021, Encyclopedia of Respiratory Medicine, Second EditionEffect of selective decontamination on antimicrobial resistance in intensive care units: A systematic review and meta-analysis
2013, The Lancet Infectious DiseasesCitation Excerpt :Finally, two groups of investigators followed up cohorts from RCTs of SDD12,41 with before-and-after studies52,86 examining changes in resistance rates before introduction of the SDD intervention and after removal of SDD after the trial. A 2 year trial in a South African ICU41 detected a reduction in cefotaxime-resistant Enterobacteriaceae (p=0·02), and no statistically significant changes in MRSA or aminoglycoside-resistant Gram-negative bacilli.52 By contrast with these findings, an ecological analysis of the 6 months after versus the 6 month before an SDD intervention in a large crossover RCT in the Netherlands showed an increase in intestinal colonisation with resistant Gram-negative bacilli; ceftazidime resistance increased from 5% to 15%, tobramycin resistance increased from 7% to 13%, and ciprofloxacin resistance increased from 7% to 13% (p<0·05 for all comparisons).86
Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation
2021, Cochrane Database of Systematic ReviewsUse of Colistin in Critically Ill Patients
2019, Advances in Experimental Medicine and BiologySelective intestinal decontamination for the prevention of early bacterial infections after liver transplantation
2016, World Journal of GastroenterologyAn Ounce of Prevention Saves Tons of Lives: Infection in Burns
2015, Surgical Infections