Biochimica et Biophysica Acta (BBA) - Biomembranes
Volume 1070, Issue 1, 18 November 1991, Pages 187-192
Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times
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The term ‘sterically stabilized’ liposomes is referring to liposomes that have long circulation time in blood irrespective of the bilayer fluidity and surface charge density and in addition show a t1/2 which is independent of dose. Such liposomes contain lipids with special headgroups such as GM1, PI, PEG-PE that contribute to their long blood residence time.
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