Journal of the American Academy of Dermatology
Congenital cutaneous candidiasis associated with respiratory distress and elevation of liver function tests: A case report and review of the literature☆,☆☆,★
Section snippets
CASE REPORT
A 3820 gm girl was born at term to a 35-year-old gravida 2 para 1 white woman who had good prenatal care. Maternal serologic screening was negative for human immunodeficiency virus, hepatitis B, and syphilis. Cultures for Chlamydia, group B streptococcus, and gonococcus were negative. There was no history of herpes simplex infection. The mother had been treated with terconazole vaginal suppositories 1 week before delivery for severe candidal vaginitis. At that time, the mother suspected that
DISCUSSION
CCC was first described by Sonnenschein et al. in 1960. 5 Fewer than 100 cases of CCC have been reported in the English-language literature. 4, 8
The pathogenesis of CCC is only partially understood. Sonnenschein et al. 5 thought that CCC might result from the combination of vaginal candidal infection, prolonged rupture of membranes, and intensive administration of antibiotics, all of which their first patient had. Most cases reported since then have followed maternal candidal vulvovaginitis,
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This article is made possible through an educational grant from the Dermatological Division, Ortho Pharmaceutical Corporation.
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Reprint requests: Franklin P. Flowers, MD, Division of Dermatology and Cutaneous Surgery, PO Box 100277, Gainesville, FL 32610-0277.
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