Electrophysiological analysis of a sensorimotor integration task

doi:10.1016/j.neulet.2007.08.061

Neuroscience Letters

Volume 426, Issue 3, 22 October 2007, Pages 155-159

https://doi.org/10.1016/j.neulet.2007.08.061 Get rights and content

Abstract

The present experiment aimed at investigating electrophysiologic changes observed as beta band asymmetry, by Quantitative Electroencephalography (qEEG), when individuals performed a reaching motor task (catching a ball in free fall). The sample was composed of 23 healthy individuals, of both sexes, with ages varying between 25 and 40 years old. All the subjects were right handed. A two-way ANOVA was applied for the statistical analysis, to verify the interaction between task moment (i.e., 2 s before and 2 s after ball's fall) and electrode (i.e., frontal, central and temporal regions). The first analysis compared electrodes placed over the somatosensory cortex. Central sites (C3–C4) were compared with temporal regions (T3–T4). The results showed a main effect for moment and position. The second analysis was focused over the premotor cortex, which was represented by the electrodes placed on the frontal sites (F3–F4 versus F7–F8), and a main effect was observed for position. Taken together, these results show a pattern of asymmetry in the somatosensory cortex, associated with a preparatory mechanism when individuals have to catch an object during free fall. With respect to task moment, after the ball's fall, the asymmetry was reduced. Moreover, the difference in asymmetry between the observed regions were related to a supposed specialization of areas (i.e., temporal and central). The temporal region was associated with cognitive processes involved in the motor action (i.e., explicit knowledge). On the other hand, the central sites were related to the motor control mechanisms per se (i.e., implicit knowledge). The premotor cortex, represented by two frontal regions (i.e., F3–F4 versus F7–F8), showed a decrease on neural activity in the contralateral hemisphere (i.e., to the right hand). This result is in agreement with other experiments suggesting a participation of the frontal cortex in the planning of the apprehension task. This sensorimotor paradigm may contribute to the repertoire of tasks used to study clinical conditions such as depression, alzheimer and Parkinson diseases.

References (35)

L.F. Basile et al.
Interindividual variability in EEG correlates of attention and limits of functional mapping
Int. J. Psychophysiol.
(2007)
H. Chapman et al.
The neural basis of selection-for-action
Neurosci. Lett.
(2007)
J.A. Coan et al.
A capability model of individual differences in frontal EEG asymmetry
Biol. Psychol.
(2006)
L.M.F. Doyle et al.
Lateralization of event-related beta desynchronization in the EEG during pre-cued reaction time tasks
Clin. Neurophysiol.
(2005)
W. Gaetz et al.
Localization of sensorimotor cortical rhythms induced by tactile stimulation using spatially filtered MEG
Neuroimage
(2006)
M. Ghilardi et al.
Patterns of regional brain activation associated with different forms of motor learning
Brain Res.
(2000)
M. Iacoboni et al.
Beyond a single area: motor control and language within a neural architecture encompassing Broca's area
Cortex
(2006)
M.T. Jurkiewicz et al.
Post-movement beta rebound is generated in motor cortex: evidence from neuromagnetic recordings
Neuroimage
(2006)
L. Leocani et al.
Event-related coherence and event-related desynchronization/synchronization in the 10 Hz and 20 Hz EEG during selfpaced movements
Electroencephalogr. Clin. Neurophysiol.
(1997)
J.F. Lubar et al.
Methylphenidate effects on global and complex measures of EEG
Pediatr. Neurol.
(1999)

H. Mushiake et al.

Activity in the lateral prefrontal cortex reflects multiple steps of future events in action plans

Neuron

(2006)

R. Oldfield

The assessment and analysis of handedness: the Edinburgh inventory

Neuropsychologia

(1971)

G. Pfurtscheller et al.

Event-related EEG/MEG synchronization and desynchronization: basic principles

Clin. Neurophysiol.

(1999)

G. Pfurtscheller et al.

Spatiotemporal patterns of beta desynchronization and gamma synchronization in corticographic data during self-paced movement

Clin. Neurophysiol.

(2003)

G. Pfurtscheller et al.

Beta rebound after different types of motor imagery in man

Neurosci. Lett.

(2005)

G. Pfurtscheller et al.

Early onset of post-movement beta electroencephalogram synchronization in the supplementary motor area during self-paced finger movement in man

Neurosci. Lett.

(2003)

J.L. Price et al.

Networks related to the orbital and medial prefrontal cortex; a substrate for emotional behavior?

Prog. Brain Res.

(1996)

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Electrophysiological analysis of a sensorimotor integration task

Abstract

Int. J. Psychophysiol.

Neurosci. Lett.

Biol. Psychol.

Clin. Neurophysiol.

Neuroimage

Brain Res.

Cortex

Neuroimage

Electroencephalogr. Clin. Neurophysiol.

Pediatr. Neurol.

Neuron

Neuropsychologia

Clin. Neurophysiol.

Clin. Neurophysiol.

Neurosci. Lett.

Neurosci. Lett.

Prog. Brain Res.