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Gender difference in relation to depression and quality of life among patients with a primary brain tumor

Published online by Cambridge University Press:  16 April 2020

Arja Mainio ,
Helinä Hakko ,
Asko Niemelä ,
John Koivukangas  and
Pirkko Räsänen
Arja Mainio*
Affiliation:
Department of Psychiatry, University of Oulu, Box 5000, 90014Oulu, Finland Department of Psychiatry, Oulu University Hospital, Box 26, 90029Oys, Finland
Helinä Hakko
Affiliation:
Department of Psychiatry, University of Oulu, Box 5000, 90014Oulu, Finland Department of Psychiatry, Oulu University Hospital, Box 26, 90029Oys, Finland
Asko Niemelä
Affiliation:
Department of Psychiatry, University of Oulu, Box 5000, 90014Oulu, Finland Department of Psychiatry, Oulu University Hospital, Box 26, 90029Oys, Finland
John Koivukangas
Affiliation:
Department of Neurosurgery, Oulu University Hospital, Box 26, 90029Oys, Finland
Pirkko Räsänen
Affiliation:
Department of Psychiatry, University of Oulu, Box 5000, 90014Oulu, Finland Department of Psychiatry, Oulu University Hospital, Box 26, 90029Oys, Finland
*
*Corresponding author. Tel.: +358 8 315 4509; fax: +358 8 315 4648. E-mail address: arja.mainio@oulu.fi (A. Mainio).
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Abstract

Objective. –

We studied the relationship between depressive symptoms and quality of life (QOL) as well as functional status in primary brain tumor patients at recurrent measurements. Differences in QOL between depressive and non-depressive samples by gender were controlled for tumor characteristics and patients' psychosocial factors.

Materials and methods. –

The data consisted of 77 patients with a primary brain tumor, 30 males and 47 females. Depression of the patients was assessed by Beck Depression Inventory (BDI) and Crown-Crisp Experiential Index (CCEI), functional status by Karnofsky Performance scale (KPS) and QOL by Sintonen's 15D before tumor operation as well as at 3 months and at 1 year from surgical operation of the tumor.

Results.

The level of QOL in females was lower compared to that of males. Depression was the main predictor for worse QOL in the patients at all measurements. Depressive patients with a benign brain tumor had significantly worse QOL versus non-depressive ones.

Discussion and conclusion. –

Decreased QOL was strongly related to depression, especially among patients with a benign brain tumor. Further studies are needed to find whether sufficient depression therapy improves the QOL of patients.

Keywords

Brain tumorDepressionFunctional statusGenderQuality of life
Type
Original articles
Information
European Psychiatry , Volume 21 , Issue 3 , April 2006 , pp. 194 - 199
Copyright
Copyright © European Psychiatric Association 2006

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