Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1863, Issue 7, July 2017, Pages 1829-1839
Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells
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Abbreviations
ACh
acetylcholine
CAC
citric acid cycle
DHE
dihydroethidium
FFAs
free fatty acids
HFD
high-fat diet
HIF-1α
hypoxic inducible factor-1α
HK
hexokinase
HUVECs
human umbilical vein endothelial cells
mPTP
mitochondrial permeability transition pore
PA
palmitate
PDH
pyruvate dehydrogenase
RAECs
rat aortic endothelial cells
TC
total cholesterol
TGs
triglycerides
VDAC1
voltage-dependent anion channel 1
Chemical compounds studied in this article
Mangiferin (PubChem CID: 5281647)
Triciribine (PubChem CID: 65399)
Palmitate (PubChem CID: 985)
Metformin (PubChem CID: 4091)
Acetylcholine (PubChem CID: 187)
Keywords
Mangiferin
Akt
Hexokinase-II
Mitochondria
Endothelium
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