Prevalence of T-Wave Inversion Beyond V1 in Young Normal Individuals and Usefulness for the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/dysplasia

doi:10.1016/j.amjcard.2004.12.060

The American Journal of Cardiology

Volume 95, Issue 9, 1 May 2005, Pages 1070-1071

https://doi.org/10.1016/j.amjcard.2004.12.060 Get rights and content

T-wave inversion in precordial leads V₁ to V₃ is present in <3% of apparently healthy subjects who are 19 to 45 years of age but is present in 87% of patients who have arrhythmogenic right ventricular cardiomyopathy/dysplasia. T-wave inversion in lead V₂ or V₃ in a young or middle-aged patients who have no apparent heart disease but do have ventricular arrhythmias of left bundle branch morphology should raise the suspicion of arrhythmogenic right ventricular cardiomyopathy/dysplasia.

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The incidence of precordial T changes has been described in athletes and in specific populations, while the etiology in a large patient population admitted to the hospital has not previously been reported.
All electrocardiograms (ECGs) read by the same physician with new (compared to prior ECGs) or presumed new (no prior ECGs) precordial T wave inversions of >1 mm (0.1 mV) in multiple precordial leads were retrospectively reviewed and various ECG, patient-related, and imaging parameters assessed. A total of 226 patients and their ECGs were initially selected for analysis. Of these, 35 were eliminated leaving 191 for the final analysis.
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Citation Excerpt :
T-wave inversions in the right precordial leads after an episode of ventricular arrythmia are typical in the differential diagnosis of arrhythmogenic cardiomyopathy. They are present in up to 87% of adult patients with arrhythmogenic cardiomyopathy,4 related to right ventricular dilatation. T-wave inversion in the lateral or inferior leads helps to identify patients with left ventricular involvement.
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Citation Excerpt :
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: This work was supported in part by Grant UO1-HL65594 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.

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EditorialPrevalence of T-Wave Inversion Beyond V1 in Young Normal Individuals and Usefulness for the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/dysplasia

Am Heart J

Am J Cardiol

Am J Cardiol

Am Heart J

The normal electrocardiogram in childhood

Arch Kreislaufforsch

Diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy: task force of the Working Group Myocardial and Pericardial Disease of the European Society of Cardiology and of the Scientific Council on Cardiomyopathies of the International Society and Federation of Cardiology

Br Heart J

Editorial
Prevalence of T-Wave Inversion Beyond V₁ in Young Normal Individuals and Usefulness for the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/dysplasia