Major ArticleImpact of StatLock securing device on symptomatic catheter-related urinary tract infection: A prospective, randomized, multicenter clinical trial
Section snippets
Study design
This prospective, randomized, multicenter clinical trial was approved by the institutional review boards of all 4 participating, tertiary care medical centers. Adult patients with SCI who were diagnosed with neurogenic bladder and required a long-term indwelling transurethral or suprapubic bladder catheter were eligible for enrollment in the study. After obtaining an informed consent from the patients or their legal guardians, enrolled patients were randomized (using a separate randomization
Patients and clinical characteristics
Of 127 enrolled patients, 9 were not followed for >10 days and, therefore, were excluded from analysis. The 9 excluded patients included 5 in the experimental group (2 voluntarily withdrew from the study and 3 developed UTI ≤10 days after enrollment) and 4 in the control group (1 withdrew from the study and 3 developed UTI ≤10 days after enrollment). A total of 118 patients (60 in the experimental group and 58 in the control group) were evaluable. The 2 groups of evaluable patients had
Discussion
Prevention of UTI, the most common health care-acquired infection, can be difficult to achieve, particularly in patients with long-term indwelling bladder catheters.15, 22 The results of this clinical trial indicate that the use of the StatLock securing device was associated with a 45% reduction in the rate of symptomatic UTI in patients with a catheter-dependent neurogenic bladder. Although this observed level of protection against UTI that was afforded by the use of the StatLock securing
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Neurogenic Lower Urinary Tract Dysfunction
2020, Braddom's Physical Medicine and RehabilitationBladder Dysfunction
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2014, Journal of Surgical ResearchCitation Excerpt :Securing devices have the potential to eliminate untoward complications associated with urethral and/or meatal erosion. A prospective randomized study by Darouiche et al. [17] looking at the impact of StatLock securing devices on CAUTIs demonstrated a 45% reduction in symptomatic UTI. We used a closed drainage system that has been demonstrated by others to significantly reduce CAUTIs [18], but the Foleys we use are standard tips with no antibacterial coating such as silver alloys [18].
Presented in part at the 15th Annual Meeting of the Society for Healthcare Epidemiology of America, Los Angeles, CA, 2005; Abstract No. 163.
Supported by funds from the Department of Veterans Affairs, Washington, DC, and by a grant from Venetec International, San Diego, CA. The funding institutions played no role in the conduct of the study and did not contribute to the decision to submit the manuscript for publication.