Retrospective study of antibiotic resistance among uropathogens from rural teaching hospital, Tamilnadu, India

doi:10.1016/S2222-1808(12)60082-6

Asian Pacific Journal of Tropical Disease

Volume 2, Issue 5, October 2012, Pages 375-380

https://doi.org/10.1016/S2222-1808(12)60082-6 Get rights and content

Abstract

Objective

To determine the community associated urinary tract infection (UTI) causing uropathogen's prevalence, antibiotic resistance pattern and the risk factors predisposing infection in Indian rural settings.

Methods

A pilot study was conducted between January and December 2010 among out patients attending rural teaching medical college hospital at Tamilnadu, India. The demographic details, culture, common antibiotic Kirby-Bauer disc diffusion assay susceptibility profiles of the isolates and the resistance analysis by WHONET 5.6 software were performed.

Results

During this surveillance study, a total number of 1 359 urinary samples were collected, among which 309 (22.78%) gave positive culture. The common uropathogens encountered were Escherichia coli (66.02%), Staphylococcus sp. (12.62%), Klebsiella sp. (5.83%), Streptococcus sp. (5.18%), Enterococcus sp. (2.59%) and Proteus sp., (2.26%). Antibiotic resistance analysis revealed the multiple drug resistance nature of the isolates to the commonly used antibiotics. It is also found that both genders at the specific age group of 40-50 were more prone to infection and seasonal variations also play an important role in their establishment.

Conclusions

The obtained results suggest that antibiotic selection for empirical treatment should be based on individual drug-sensitive test results. There is also an urgent need to develop a new combination of chemotherapeutic agents and awareness on antibiotic use for the effective UTI management in rural settings.

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: Available online 28 October 2012

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Document headingRetrospective study of antibiotic resistance among uropathogens from rural teaching hospital, Tamilnadu, India

Abstract

Objective

Methods

Results

Conclusions

J Nurse Pract

J Infect Public Health

Med

Int J Antimicrob Agents

Diag Microbiol Infect Dis

EAU Update Series

J Infect

Lancet

J Urol

Diag Microbiol Infect Dis

Int J Infect Dis

Lancet Infect Dis

J Infect

Diag Microbiol Infect Dis

Asian Pac J Trop Biomed

Predominant isolates of urinary tract pathogens and their antimicrobial susceptibility patterns in Gondar university teaching hospital, Northwest Ethiopia

Ethiop Med J

Diversity among 2481 Escherichia coli from women with community acquired lower UTIs in 17 countries

J Antimicrob Chemother

Current microbiological and clinical aspect of urinary tract infection

Eur Urol

Document heading
Retrospective study of antibiotic resistance among uropathogens from rural teaching hospital, Tamilnadu, India