Effect of temperature on the release rate of biomolecules from thermally reversible hydrogels☆
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Cited by (76)
Swelling of poly(N-isopropylacrylamide) P(NIPA)-based hydrogels with bacterial-synthesized prodigiosin for localized cancer drug delivery
2016, Materials Science and Engineering CCitation Excerpt :The uptake, storage and delivery of cancer drugs can be facilitated by the use of gels [15–17]. These include: environmentally-sensitive gels that can respond to local stimuli, such as temperature, pH, electric fields and solvent composition [18–21]. The swelling and controlled release of cancer drugs [22,23] from such gels can, therefore, provide the basis for the design of implantable biomedical systems for the localized treatment of cancer.
Prodigiosin release from an implantable biomedical device: Kinetics of localized cancer drug release
2014, Materials Science and Engineering CCitation Excerpt :The increasing incidence of cancer [1] has stimulated research on the development of novel implantable devices for the localized treatment of cancer [2–5].
Low temperature plasma vapor treatment of thermo-sensitive poly(N-isopropylacrylamide) and its application
2013, Applied Surface ScienceCitation Excerpt :PBT is a hydrophobic material that frequently needs to be treated before application [17]. In this study of PNIPAAm treated and untreated glass slides and PS petri dish, with considering of the temperature of the human body is close to the LCST, these results are valuable for further application on the thermo-sensitive textile materials [18–22]. In the study of PNIPAAm was deposited onto PBT melt-blown nonwoven, it was found that the water permeability can be significantly modified by changing of the temperature at around LCST.
Investigation of swellable poly (N-isopropylacrylamide) based hydrogels for drug delivery
2011, Materials Science and Engineering CCitation Excerpt :Besides specific polymer matrix designs for hydrogel drug delivery, efforts have been made to develop mathematical models for the control of the drug release mechanisms in drug delivery systems [20–22]. Fick's first and second laws have been used to describe diffusion with constant (or time dependent) diffusion coefficients in diffusion-controlled drug release systems [1,23]. However, it is usually difficult to obtain analytical solutions when drug release occurs from complex geometries.
Effects of temperature on diffusion from PNIPA-based gels in a BioMEMS device for localized chemotherapy and hyperthermia
2011, Materials Science and Engineering C
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Paper presented at the ACS Regional Meeting held in Portland, Oregon, June 1986