Relationship between musculoskeletal symptoms and blood markers of oxidative stress in patients with chronic fatigue syndrome
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2019, Biochemical PharmacologyCitation Excerpt :Although the etiology of this disease is still unknown, recent studies have indicated the implication of oxidative stress, mitochondrial dysfunction and inflammation in the pathophysiology of FM [213,214]. For instance, different studies have observed increased oxidative stress and deregulated antioxidative parameters in patients with FM [37,213,215], events that have been associated with musculoskeletal manifestations like fatigue and pain [216]. Likewise, levels of altered lipid peroxidases were correlated with clinical symptoms and severity of FM [213].
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