Elsevier

The Lancet

Volume 327, Issue 8494, 14 June 1986, Pages 1344-1346
The Lancet

RADIOIMMUNOASSAY OF RELAXIN IN PREGNANCY WITH AN ANALOGUE OF HUMAN RELAXIN

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Abstract

A radioimmunoassay for relaxin was developed in which a synthetic analogue of human relaxin was used as standard, tracer, and immunogen. Relaxin could not be measured in sera from men or non-pregnant women, but was measurable in pregnant women from the tenth week of gestation until term. Concentrations ranged from 0·19-1·18 ng/ml, with highest levels measured in the first trimester.

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