Alphaherpesvirus Latency: Its Role in Disease and Survival of the Virus in Nature
References (267)
- et al.
Mutagenesis of a cAMP response element within the latency-associated promoter of HSV-1 reduces adrenergic reactivation
Virology
(1997) - et al.
The latency related gene of bovine herpesvirus 1 inhibits the activity of immediate early transcription unit 1
Virology
(1992) - et al.
Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specificity localize at subnuclear sites of DNA replication
Cell
(1993) - et al.
A serological survey of bovine herpesvirus-1 infection in selected dairy herds in northern and central Italy
Comp. Immun. Microbiol. Infect. Dis.
(1997) - et al.
Alternative splicing of a neural-specific Src mRNA (Src+) is a rapid and protein synthesis-independent response to neural induction in Xenopus laevis
Dev. Biol.
(1993) - et al.
Behavioral effects of neonatal herpes simplex virus type 1 infection of mice
Neurotoxicol.-Teratol.
(1988) - et al.
An HSV-1 mutant lacking the LAT TATA element reactivates normally in explant cocultivation
Virology
(1993) - et al.
A novel macromolecular structure is a target of the promyelocytic-retinoic acid receptor oncoprotein
Cell
(1994) Transcription of the HSV-1 genome in neurons in vivo
Sem. Virol.
(1994)- et al.
Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death
Neuron
(1994)
Bovine herpesvirus 1–induced apoptosis occurs at the G0/G1 phase of the cell cycle
Virology
Rules to replicate by
Cell
Herpes simplex virus latent phase transcription facilitates in vivo reactivation
Virology
DNA of bovine herpesvirus type 1 in the trigeminal ganglia of latently infected calves
Am. J. Vet. Res.
Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by nonisotopic in situ hybridization
J. Gen. Virol.
Disruption of the 5′ and 3′ splice sites flanking the major latency-associated transcripts of herpes simplex virus type 1: Evidence for alternative splicing in lytic and latent infection
J. Gen. Virol.
Recovery of herpes simplex virus from human trigeminal ganglions
New Engl. J. Med.
Herpesvirus hominis: Isolation from human trigeminal ganglion
Science
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1
J. Virol.
Localization of cis-acting sequence requirements in the promoter of the latency-associated transcript of herpes simplex virus type 1 required for cell-type-specific activity
J. Virol.
Binding and repression of the latency-associated promoter of herpes simplex virus by the immediate early 175K protein
J. Gen. Virol.
Seroprevalence of and risk factors for antibodies to herpes simplex viruses, hepatitis B, and hepatitis C among southwestern Hispanic and non-Hispanic white women
Sex Transm. Dis.
The latency associated transcripts (LAT) of herpes simplex virus: Still no end in sight
J. Neurovirol.
A herpes simplex virus type 1 latency-associated transcript mutant reactivates with normal kinetics from latent infection
J. Virol.
Molecular analysis of herpes simplex virus type 1 during epinephrine-induced reactivation of latently infected rabbits in vivo
J. Virol.
A 348 base pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation
J. Virol.
Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region
J. Virol.
Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1
J. Virol.
Overexpression of cyclin A in the mammary glands of transgenic mice results in the induction of nuclear abnormalities and increased apoptosis
Cell Growth Different.
Localization of cis-acting sequences in the latency-related promoter of bovine herpesvirus 1 which are regulated by neuronal cell type factors and immediate-early genes
J. Virol.
Open reading frame P — A herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA
Proc. Natl. Acad. Sci. U.S.A.
Detection and characterization of latent HSV RNA by in situ and Northern blot hybridization in guinea pigs
Virology
A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1
J. Virol.
Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1
J. Virol.
Interaction of the viral activator protein ICP4 with TFIID through TAF250
Mol. Cell. Biol.
Dystrophin gene transcribed from different promoters in neuronal and glial cells
Nature
A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus
J. Virol.
Two herpes simplex virus type 1 latency-active promoters differ in their contribution to latency-associated transcript expression during lytic and latent infection
J. Virol.
The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited passage isolates but not in strain 17syn+
J. Virol.
Mapping of herpes simplex virus-1 neurovirulence to gamma 34.5, a gene nonessential for growth in culture
Science
Temporal regulation of herpes simplex virus type 1 transcription: Location of transcripts on the viral genome
Cell
Thymidine kinase negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate
Proc. Natl. Acad. Sci. U.S.A.
Varicella-zoster virus (VZV) transcription during latency in human ganglia: Detection of transcripts mapping to genes 21, 29, 62, and 63 in a cDNA library enriched for VZV RNA
J. Virol.
Infections with herpes simplex viruses
New Engl. J. Med.
Latent herpes simplex virus in human trigeminal ganglia. Detection of an immediate early “anti-sense” transcript by in situ hybridization
New Engl. J. Med.
Patterns of gene expression and sites of latency in human nerve ganglia are different for varicella-zoster and herpes simplex viruses
Proc. Natl. Acad. Sci. U.S.A.
Characterization of herpes simplex virus type 2 latency-associated transcription in human sacral ganglia and in cell culture
J. Infect. Dis.
Role of cell-mediated immunity in the recovery of cattle from primary and recurrent infections with infectious bovine rhinotracheitis virus
Infect. Immunol.
RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice
Proc. Natl. Acad. Sci. U.S.A.
Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome
J. Virol.
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2021, Vitamins and HormonesCitation Excerpt :The LAT locus expresses multiple transcripts, six micro-RNAs, and two small non-coding RNAs (Peng, Vitvitskaia, Carpenter, Wechsler, & Jones, 2008; Umbach et al., 2008, 2009). LAT inhibits apoptosis and viral gene expression (Ahmed, Lock, Miller, & Fraser, 2002; Branco & Fraser, 2005; Inman, Lovato, Doster, & Jones, 2001; Inman, Perng, et al., 2001; Inman, Zhang, Geiser, & Jones, 2001; Perng et al., 2000; Thompson & Sawtell, 2001), which protects neurons from cell death and promotes establishment and maintenance of latency (Jones, 1998, 2003; Perng & Jones, 2010). Further support for LAT maintaining latency comes from a study demonstrating that shedding of a LAT null mutant dramatically declines following multiple rounds of heat stress-induced reactivation in a mouse model of latency (Thompson & Sawtell, 2011).