Cyclosporin-A inhibits human endothelial cells proliferation through interleukin-6-dependent mechanisms
References (47)
- et al.
Cell
(1991) - et al.
Lancet
(1988) Cell
(1990)- et al.
Exp. Cell Res.
(1993) - et al.
Biochem. Biophys. Res. Commun.
(1989) - et al.
Toxicol. Lett.
(1985) - et al.
J. Biol. Chem.
(1992) - et al.
Cell. Immunol.
(1989) - et al.
Blood
(1994) - et al.
J. Biol. Chem.
(1995)
J. Biol. Chem.
(1995)
Science
(1989)
EMBO J.
(1990)
J. Heart Transplant.
(1989)
N. Engl. J. Med.
(1984)
Transplantation
(1993)
Transplantation
(1987)
Br. J. Haematol.
(1985)
Am. J. Med.
(1988)
N. Engl. J. Med.
(1990)
Pharmacol. Rev.
(1989)
Transplantation
(1988)
Biochem. Pharmacol.
(1990)
Cited by (22)
Impaired endothelial progenitor cell recruitment may contribute to heart transplant microvasculopathy
2011, Journal of Heart and Lung TransplantationCitation Excerpt :Cyclosporine was seen to affect a range of vascular progenitor biologic functions. Cyclosporine has previously been shown to inhibit endothelial cell proliferation in the context of increased interleukin-6 protein and messenger RNA expression and decreased nitric oxide production.20 Other immunosuppressive drugs, such as mammalian target of rapamycin inhibitors, can also have a potent inhibitory effect on circulating vascular progenitor cells.21
Cyclosporine decreases vascular progenitor cell numbers after cardiac transplantation and attenuates progenitor cell growth in vitro
2005, Journal of Heart and Lung TransplantationCyclosporine nephrotoxicity
2003, Seminars in NephrologyRole of endothelin-1 in microvascular dysfunction caused by cyclosporin A
2003, Journal of the American College of Surgeons
Copyright © 1997 Published by Elsevier Inc.