Short communicationThe PPAR-γ ligand 15-deoxyΔ12,14 prostaglandin J2 reduces the liver injury in endotoxic shock
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Acknowledgments
M.C. is supported by Academy of Finland, Paavo Nurmi Foundation and Farmos Research Foundation.
References (7)
- et al.
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation
Br. J. Pharmacol.
(2002) - et al.
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by Gram-negative and Gram-positive bacterial stimuli
Shock
(2003) - et al.
The peroxisome proliferator activated receptor-gamma is a negative regulator of macrophage activation
Nature
(1998)
There are more references available in the full text version of this article.
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