Septic shock during pregnancy
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Cited by (55)
Critical care in obstetrics
2022, Best Practice and Research: Clinical AnaesthesiologyCitation Excerpt :The pathophysiology of sepsis-induced cardiac dysfunction is a thoroughly investigated process that is thought to occur from a complex set of cardio-depressant effects of inflammatory interleukins, oxidative stress, mitochondrial dysfunction, and ultimately leading to necrosis apoptosis of cardiomyocytes [85,86]. In autopsy studies examining pregnant (or recently pregnant women) who have died of sepsis, left ventricular failure dysfunction was found in 50–80% of women [87,88]. The incidence of cardiovascular dysfunction in maternal sepsis, however, is poorly understood and remains a topic of active investigation.
Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation
2017, American Journal of Obstetrics and GynecologyCitation Excerpt :Clinical chorioamnionitis is a well-known risk factor for adverse maternal and perinatal outcomes.12-14 Affected mothers have an increased rate of endometritis,2,15 postoperative wound infections,2,16 sepsis,17,18 disseminated intravascular coagulation,19 septic pelvic thrombophlebitis,20,21 postpartum hemorrhage,22 pelvic abscess,2 and other complications.2,4,23-26 Neonatal complications include congenital sepsis11,25,27-34 as well as localized infections such as pneumonia,27,28 dermatitis,35 and otitis media.36
Fever and pregnancy
2016, Anaesthesia Critical Care and Pain MedicineCitation Excerpt :However, if uterine content is the supposed origin of sepsis, delivery of the foetus must be considered promptly. In the study by Lee et al. [46] in 1988, foetal extraction had to be done in 40% of cases. Termination of pregnancy can be indicated for obstetrical reason, but in all other cases, foetal extraction has not proven effective for maternal prognosis, except during maternal cardiac arrest.
Managing the risks of sepsis in pregnancy
2013, Best Practice and Research: Clinical Obstetrics and GynaecologyCitation Excerpt :A study in the Netherlands9 found a case fatality rate of 7.7%. Other studies have reported rates of 12% overall maternal mortality in women admitted to the intensive care unit and 20–28% maternal mortality in those with septic shock.18,19 The UK Obstetric Surveillance system is currently carrying out a population-based case-control study to estimate the incidence of severe maternal sepsis and investigate risk factors, causes and outcomes.
Maternal Sepsis
2013, Obstetrics and Gynecology Clinics of North AmericaCitation Excerpt :If one adds in the rates of pyelonephritis, sepsis is not at all uncommon. Pyelonephritis accounts for 3% to 4% of all antepartum admissions5 and makes up the largest proportion of the overall rare obstetric cases complicated by severe septic shock in the United States.6,7 In obstetrics, this is not a common event.
Severe sepsis and pregnancy
2012, Praticien en Anesthesie Reanimation