Chapter 1 - The Dose–Response Revolution: How Hormesis Became Significant: An Historical and Personal Reflection

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Abstract

The chapter tells the story of how hormesis emerged from a marginalized dose–response concept that had been significantly weakened by its historical association with homeopathy to become widely recognized as a central concept in evolution, biology, toxicology, and medicine. The chapter is set within the framework of a personal reflection of the author concerning key aspects of how this dose–response revolution occurred and the nature of its biological and biomedical significance.

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